Week 1 Favorites in NFL: Philadelphia Eagles and Kansas City Chiefs lead the way in opening season odds
Kickoff to the 2025 NFL Season!
The first week of the 2025 regular season promises some exciting matchups, highlighted by games in Philly, Sao Paulo, Buffalo, and Chi-town. Bookies are leaning towards home teams, as lines were released last Wednesday.
The Philly Eagles, Super Bowl champs, are favored by 7 points over the Cowboys in the 2025 Kickoff Game. The only game of Week 1 with a total points score under 40 sees the Pittsburgh Steelers as road favorites against the NY Jets.
Here's a rundown of the odds (courtesy of FanDuel) for all games scheduled from Sept 4-8:
Thursday, Sept 4
Dallas Cowboys at Philadelphia Eagles (-6.5)
8:20 p.m. ET on NBC, Lincoln Financial Field, Philadelphia
Money line: Eagles -330, Cowboys +265
Total: 46.5 points
Friday, Sept 5
Kansas City Chiefs (-2.5) vs. LA Chargers
8 p.m. ET on YouTube, Corinthians Arena, Sao Paulo
Money line: Chiefs -142, Chargers +120
Total: 44.5 points (Under -105 odds)
Sunday, Sept 7
NY Giants at Washington Commanders (-7)
1 p.m. ET, Northwest Stadium, Landover, Md.
Money line: Commanders -350, Giants +280
Total: 45.5 points
Tampa Bay Bucs (-1.5) at Atlanta Falcons
1 p.m. ET, Mercedes-Benz Stadium, Atlanta
Money line: Bucs -126, Falcons +108
Total: 48.5 points
Carolina Panthers at Jacksonville Jaguars (-2.5)
1 p.m. ET, EverBank Stadium, Jacksonville
Money line: Jaguars -144, Panthers +122
Total: 46.5 points
Miami Dolphins at Indianapolis Colts (-1)
1 p.m. ET, Lucas Oil Stadium, Indianapolis
Money line: Dolphins -104, Colts -116
Total: 45.5 points
Las Vegas Raiders at New England Patriots (-2)
1 p.m. ET, Gillette Stadium, Foxborough, Mass.
Money line: Patriots -156, Raiders +132
Total: 43.5 points
Pittsburgh Steelers (-3) at NY Jets
1 p.m. ET, MetLife Stadium, East Rutherford, NJ
Money line: Steelers -156, Jets +132
Total: 39.5 points
Cincinnati Bengals (-5.5) at Cleveland Browns
1 p.m. ET, Huntington Bank Field, Cleveland
Money line: Bengals -240, Browns +198
Total: 45.5 points
AZ Cardinals (-4.5) at New Orleans Saints
1 p.m. ET, Caesars Superdome, New Orleans
Money line: Cardinals -200, Saints +168
Total: 41.5 points
SF 49ers (-1.5) at Seattle Seahawks
4:05 p.m. ET, Lumen Field, Seattle
Money line: 49ers -124, Seahawks +106
Total: 45.5 points
Tenn Titans at Denver Broncos (-7)
4:05 p.m. ET, Empower Field at Mile High, Denver
Money line: Broncos -350, Titans +280
Total: 41.5 points
Detroit Lions (-1.5) at Green Bay Packers
4:25 p.m. ET, Lambeau Field, Green Bay, WI
Money line: Lions -122, Packers +104
Total: 49.5 points
Houston Texans at LA Rams (-2.5)
4:25 p.m. ET, Sofi Stadium, Inglewood, CA
Money line: Rams -146, Texans +124
Total: 46.5 points
Baltimore Ravens at Buffalo Bills (-1.5)
8:20 p.m. ET on NBC, Highmark Stadium, Orchard Park, NY
Money line: Bills -122, Ravens +104
Total: 51.5 points
Monday, Sept 8
Minnesota Vikings (-1.5) at Chicago Bears
8:15 p.m. ET on ESPN/ABC, Soldier Field, Chicago
Money line: Vikings -110, Bears -106
Total: 45.5 points
Insights: FanDuel's betting lines include point spreads, over/under totals, and moneylines for every matchup, like the Kansas City Chiefs vs. LA Chargers with an Under 44.5 points total at around -105 odds. Experts' win total bet analyses for teams such as the Chicago Bears, NY Giants, SF 49ers provide insight into betting sentiment (source: FanDuel). Real-time odds for Week 1 games can be found on platforms like RotoWire (source: RotoWire).
- The Philadelphia Eagles, Super Bowl champions, are favored by 7 points over the Cowboys in the 2025 Kickoff Game, as per FanDuel's odds.
- The only game of Week 1 with a total points score under 40 is the Pittsburgh Steelers vs. NY Jets, with the Steelers being road favorites, also according to FanDuel's odds.
- In their matchup, the NY Giants are underdogs against the Washington Commanders by 7 points, as shown in FanDuel's odds.
- The Las Vegas Raiders are facing the New England Patriots in the NFL season opener, with the Patriots being favored by 2 points, according to FanDuel's odds.
