Time to take on the Cleveland Guardians, as the Boston Red Sox set off on their journey! Let's dive into our MLB predictions for this Red Sox-Guardians showdown, shall we?
Red Sox versus Guardians Forecast, Odds, Selection – 25th April 2025 (Subscription Required)
The Red Sox stand at 14-12 in the AL East, having split their series with the Seattle Mariners. They'll have one more go at the Mariners before heading to face the Guardians. On the other hand, the Guardians, with a record of 14-10 in the AL Central, have recently seen their five-game winning streak come to an end. They managed to take two out of three from the New York Yankees at home before this series.
The Starting Lineup: Tanner Houck vs. Ben Lively
Tanner Houck (0-2, 7.66 ERA, 1.66 WHIP) takes the mound for the Red Sox.
In his last outing, Houck went six innings, conceding three hits, two walks, and a home run. Unfortunately, he took no decision as the Red Sox lost to the White Sox 8-4. When playing away from home, Houck hasn't fared well, posting a 13.50 ERA and a .400 opponent batting average.
Ben Lively (1-2, 3.86 ERA, 1.25 WHIP) will be the Guardians' starting pitcher.
Lively's last start saw him going 5.1 innings and striking out three batters without giving up a run to the Pittsburgh Pirates. He's been more effective at home, owning a 3.27 ERA and a .250 opponent batting average.
Let's Check the Numbers: MLB Odds
Here are the MLB odds for this Red Sox-Guardians game, courtesy of FanDuel:
- Boston Red Sox: -1.5 (+155)
- Moneyline: -108
- Cleveland Guardians: +1.5 (-188)
- Moneyline: -108
- Over: 8.5 (-120)
- Under: 8.5 (-102)
Catch the Action LIVE!
Time: 7:10 PM ET/ 4:10 PM PT
TV: Apple TV
Boston's Batters: Ready to Shine
Alex Bregman leads the Red Sox this year, hitting a stellar .310 with a .381 OBP. He's off to a strong start with ten doubles, four home runs, 19 RBIs, and 16 runs. Alongside him, Trevor Story has also shone, hitting .309 with a .343 OBP.
In addition to these standouts, Wilyer Abreu has excelled at scoring runs (15) and notching six doubles, four home runs, 15 RBIs, and four stolen bases. Rafael Devers has been productive, despite his low batting average (.202), with a .342 OBP, seven doubles, two home runs, 14 RBIs, and 15 runs scored.
Cleveland's Bats: A Force to Reckon With
Kyle Manzardo has taken the lead for the Guardians, hitting a modest .219 but with a impressive .326 OBP. He has already amassed three doubles, a triple, seven home runs, 18 RBIs, and 12 runs. Alongside Manzardo, Steven Kwan has had a fantastic year, hitting an impressive .337 with a .394 OBP. Kwan has also contributed with three doubles, five home runs, 14 RBIs, four stolen bases, and 17 runs.
Meanwhile, Jose Ramirez and Gabriel Arias have seen impressive inroads this season, with Ramirez hitting .265 and Arias managing .270. Furthermore, Carlos Santana** has been solid, compiling two doubles, two home runs, six RBIs, and 11 runs scored.
The Final Pick: Guardians to Take the Win!
Tanner Houck's poor form this season, with a 7.66 ERA and allowing at least one home run in four of his five starts, gives Cleveland's offense a prime opportunity to capitalize. Despite Lively's effectiveness this year, the Guardians' momentum and a home-field advantage should be enough to tip the scales in their favor.
Final Prediction: Go with the Guardians ML (-108) to secure the win at home.
- The Red Sox and the Guardians are set to clash, with Tanner Houck starting for the Boston team, disbelaying a 7.66 ERA and struggling on the road.
- Ben Lively will be on the mound for the Guardians, displaying a 3.86 ERA and performing better at home.
- In MLB odds, the Guardians are favored to win at home, with the ML at -108, and the over/under set at 8.5 runs.
- Alex Bregman, Trevor Story, Wilyer Abreu, and Rafael Devers are among the Red Sox batters who have had a strong start to the season, contributing to their offensive numbers.
- Kyle Manzardo, Steven Kwan, Jose Ramirez, Gabriel Arias, and Carlos Santana are Cleveland's standout batters, providing a force to be reckoned with in the Red Sox-Guardians matchup. Predicting a Guardians win based on Tanner Houck's struggles and the Guardians' momentum and home-field advantage.


