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Rams vs 49ers: Thursday Night Football Week 5 Preview

Can Brock Purdy and the 49ers upset Matthew Stafford and the Rams in this crucial NFC West matchup? Don't miss this key divisional showdown.

In this image I see the logo of a football and I see words written and I see 2 stars.
In this image I see the logo of a football and I see words written and I see 2 stars.

Rams vs 49ers: Thursday Night Football Week 5 Preview

Thursday Night Football in Week 5 presents an exciting NFC West matchup between the San Francisco 49ers and Los Angeles Rams at SoFi Stadium. Kickoff is at 8:15 p.m. ET. Dimers' simulations give the Rams a 73% chance of winning, but the spread and total are essentially coin flips at 50-50.

Brock Purdy is forecast to throw for 243 yards for the 49ers, with Christian McCaffrey leading the rushing game and a 54.5% chance of scoring a touchdown. For the Rams, Matthew Stafford is expected to pass for 241 yards, with Puka Nacua projected as his top target at 99 receiving yards. Kyren Williams holds a 57.3% chance of finding the end zone and is projected to rush for 73 yards.

Oddsmakers have the Rams listed as 7-point favorites with a strong -325 moneyline, while the 49ers are +270 underdogs. The total for the matchup sits at 46.5 points, suggesting a balanced game with opportunities on both sides of the ball.

This marquee NFC West showdown serves as a key measuring stick for both teams as the season progresses. With divisional stakes on the line, fans can expect a closely contested game despite Dimers' projections favoring the Rams.

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