Overview of Each New San Francisco 49er Player Joining the Team...
The San Francisco 49ers are gearing up for their preseason opener, scheduled for 5:30 p.m., and the team's roster is shaping up to be an exciting mix of established stars and promising newcomers.
Key Players
Quarterbacks Brock Purdy and Mac Jones will lead the charge, while running backs Christian McCaffrey, Isaac Guerendo, Jordan James (who will miss the preseason opener due to a finger injury), Patrick Taylor, and fullback Kyle Juszczyk form a formidable ground game. Wide receivers Brandon Aiyuk (currently on injured reserve) and promising player Junior Bergen, who earned a roster spot opportunity, are also key figures. Rookies Connor Colby, Drew Moss (OL), and Upton Stout (nickelback contender) are set to make their mark on the depth.
Injuries and Roster Moves
Unfortunately, Brandon Aiyuk will start the year on injured reserve, Kuris Rourke is also on IR, and Andre Dillard's injury status is uncertain, possibly placing him on the Physically Unable to Perform (PUP) list to begin the year. Sam Okuayinonu and Malik Mustapha will start the year on the PUP list. Kevin Givens is injured but expected to make the 53-man roster as his injury is not season-ending.
Other notable roster moves due to injuries and performance include Carter Bradley potentially not staying on the practice squad after his preseason performance, the promotion of Junior Bergen ahead of veteran Russell Gage, and battles at linebacker and defensive tackle with several rookies and vets competing for spots.
Top Draft Pick Sidelined
The 49ers' top draft pick, Mykel Williams, will miss the preseason opener due to a knee injury.
For the latest news and updates on the San Francisco 49ers, stay tuned to the Bay Area News Group.
Note: This overview reflects the 49ers' current roster and injury status following their 2025 preseason opener as of early August 2025. The article was written by Cam Inman.
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The San Francisco 49ers' preseason opener will see the American-football duo of Brock Purdy and Mac Jones leading the team, with Christian McCaffrey, Isaac Guerendo, Jordan James (injured), Patrick Taylor, and Kyle Juszczyk taking charge of the ground game, while Brandon Aiyuk (injured reserve) and Junior Bergen are key figures in the air game. Unfortunately, the team's top draft pick, Mykel Williams, will miss the preseason opener due to a knee injury.
