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NFL Game 13 Odds for 49ers vs. Bears, Forecast, and Betting Selection

Struggling San Francisco 49ers and Chicago Bears face another game week, despite dismal season performance. Here's a look at our NFL betting outlook for Week 13.

NFL Matchup: 49ers vs. Bears in Week 13 Betting Odds and Analysis for Wagers
NFL Matchup: 49ers vs. Bears in Week 13 Betting Odds and Analysis for Wagers

NFL Game 13 Odds for 49ers vs. Bears, Forecast, and Betting Selection

In the upcoming Week 13 NFL game of the 2025 season between the San Francisco 49ers and Chicago Bears, betting trends and outlook are shaping up to favor the 49ers.

The 49ers, with Brock Purdy at quarterback and Christian McCaffrey's rushing potential, are seen as a strong contender for the season. Betting markets have the 49ers with over 10.5 wins at +110, and they are considered a solid NFC contender with odds of +1000 to win the NFC. San Francisco's recent games, particularly those from Week 12 onwards, tend to have totals going over, with a 15-6 record on overs in the last three years for that part of the schedule.

On the other hand, the Chicago Bears, despite offseason improvements such as the acquisition of quarterback Caleb Williams and enhancements to their offensive line and coaching staff, face more cautious betting markets. The Bears are projected to have around 8.5 wins for the season, with the "over" on wins slightly favored (+125). They face a tough schedule and are favorites in only six of their 17 regular-season games, signaling skepticism from oddsmakers despite internal optimism in Chicago.

Historical and situational context also indicate that the Bears have struggled against NFC North rivals recently, with a 7-23 record since 2020, including 2-13 at home.

MyBookie NFL, a popular platform for NFL betting, offers a wide range of odds and lines, including NFL Odds and Lines, NFL Playoff Odds, Super Bowl Odds, AFC Champion Odds, and NFC Champion Odds. However, as of the opening NFL betting lines, the details for the 49ers vs. Bears game have not been provided.

San Francisco's NFL betting trends show that they are 1-4 ATS in the last 5 games, 2-23 SU in the last 25 games, and the total went OVER in 14 of San Francisco's last 21 games on the road. Chicago's trends show that they are 1-4 SU in the last 5 games, 8-2-1 ATS in the last 11 games at home, and the total went UNDER in 4 of Chicago's last 6 games at home.

In summary, betting trends favor the 49ers as the stronger side with optimistic win total bets and a history of overs late in the schedule, while the Bears are improving but face tougher odds and tougher competition, making the matchup potentially skewed in the 49ers’ favor for bettors. Exact Week 13 lines will depend on injury updates and market moves closer to game day. Users can download the MyBookie NFL app and set reminders for upcoming games to stay updated on the latest odds and lines.

  1. With a strong performance from Brock Purdy and the potential of Christian McCaffrey's rushing, the San Francisco 49ers, who are seen as a strong contender for the season, are also favored in the upcoming Week 13 NFL game against the Chicago Bears, according to betting trends.
  2. Despite the offseason improvements made by the Chicago Bears, such as the acquisition of Caleb Williams and enhancements to their offensive line and coaching staff, the betting markets show that they face more skepticism, with the 49ers considered as the possibly stronger side in the upcoming Week 13 game.

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