MLB Matchup Wager: Mariners opposing Red Sox, offering odds at +332 for a combined wager today
Casual Baseball Parlay Picks for April 22
Take a swing at our same-game parlay for the Mariners vs Red Sox showdown at Fenway Park, kicking off at 6:45 p.m. ET. This matchup presents a prime opportunity to ride pitching strength and seize strategic prop bets.
Mariners vs Red Sox Same-Game Parlay Today
Game Time: 6:45 p.m. ET
| Bet | Odds || --- | --- || Scoreless 1st Inning (NRFI) | -115 || Miller 4+ Strikeouts | -200 || Campbell OVER 0.5 Hits | -185 || Overall | 332 |
Odds from bet365
NRFI
Parlay Pick No. 1: Scoreless 1st (NRFI)
-115
Bryce Miller has been unstoppable in the first inning this season, going 4-0 in NRFI situations while only allowing two hits in the opening frame. Brayan Bello, while yet to make his 2025 debut, finished the previous year strong in early innings, limiting opponents to a .194 average in the first inning over his final few starts. Both lineups have struggled to score in the first, making this a solid foundation for our parlay.
Parlay Pick No. 2: Miller 4+ Strikeouts
Miller 4+ Strikeouts
Miller's arsenal of a fastball-slider combo has been dominating hitters all season, with two outings of 4+ strikeouts already. The Red Sox lineup, featuring several whiff-prone hitters against right-handers, enters this bout with a 24% strikeout rate. Miller's swing-and-miss repertoire, especially his wipeout slider, should leave the Red Sox chasing pitches out of the zone.
-200
Parlay Pick No. 3: Campbell Over 0.5 Hits
Kristian Campbell has been one of the few shining stars in the struggling Red Sox offense, batting .301. Against Miller, Campbell has shown a disciplined approach at the plate and remains a reliable option to make contact. With Miller's dominance but vulnerability to contact, Campbell makes for a strong addition to our parlay.
Campbell OVER 0.5 Hits
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-185
For those brave enough to take it up a notch, consider these riskier plays:- Jorge Polanco HR- Jarren Duran Over 1.5 Bases
332
Odds would approximate +1200 to +1800 for this 5-leg parlay.
Overall
In the Mariners vs Red Sox matchup at 6:45 p.m. ET, consider the same-game parlay that includes the Scoreless 1st Inning (NRFI) at odds of -115, Miller 4+ Strikeouts at odds of -200, and Campbell OVER 0.5 Hits at odds of -185. This parlay is based on Bryce Miller's stellar first-inning performance and Brayan Bello's strong end to the previous season. Campbell, with his disciplined approach at the plate, could make contact against Miller. If you're willing to take a higher risk, consider adding Jorge Polanco HR and Jarren Duran Over 1.5 Bases to your bet slip at approximate odds of +1200 to +1800 for this 5-leg parlay. Keep in mind that this parlay involves betting sites like bet365, and patrons should bet responsibly.

