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MLB Matchup Prediction: Brewers against Pirates on August 13, Forecasted Outcomes, Betting Lines, and Top Picks from a Reliable Model

Sports simulation model on our site predicts Pittsburgh Pirates will face Milwaukee Brewers at American Family Field on Wednesday, with its MLB picks favoring the specified matchup.

MLB Game Preview for August 13, 2025: Brewers against Pirates, Predictions and Best Bets Based on a...
MLB Game Preview for August 13, 2025: Brewers against Pirates, Predictions and Best Bets Based on a Trusted Model

MLB Matchup Prediction: Brewers against Pirates on August 13, Forecasted Outcomes, Betting Lines, and Top Picks from a Reliable Model

Milwaukee Brewers Favored to Extend Winning Streak Against Struggling Pittsburgh Pirates

The Milwaukee Brewers are set to host the Pittsburgh Pirates in the final game of a six-game homestand, with the Brewers aiming to extend their impressive winning streak to 12 games.

The Brewers have been in outstanding form, with a home record of 41-20, and they have been dominating offensively, averaging over 8 runs per game during their current winning streak. In contrast, the Pirates have struggled significantly, particularly on offense and with injuries such as the absence of shortstop Oneil Cruz.

According to the latest betting odds, the Brewers are favored on the moneyline with odds ranging roughly from -139 up to -283, indicating a strong probability to win. The Pirates, on the other hand, are underdogs with positive moneyline odds between +117 and +168. The run line generally favors the Brewers at -1.5 runs, signaling the expectation that Milwaukee will win by at least two runs.

The total runs bet leans toward the over, given the Brewers’ high scoring ability. The over/under total runs is set around 6.5 to 8 runs, with some models and experts predicting a final score of around 7-2 in favor of the Brewers.

Brandon Woodruff, who boasts a 4-0 record and a 2.29 ERA this season, will take the mound for the Brewers. Rookie left fielder Isaac Collins, who has been in exceptional form this year, is expected to continue his impressive performance. In his last game against the Pirates, Collins was 2-for-5 with a double and a triple, and he recently hit a walk-off home run against the New York Mets.

Right-hander Mitch Keller (5-10, 3.86 ERA) is expected to start for the Pittsburgh Pirates. The Brewers have won five of the past six meetings with the Pirates and lead the National League Central with the best record in MLB.

The first pitch of the game is scheduled for 2:10 p.m. ET at American Family Field in Milwaukee. Betting enthusiasts are advised to consider the Brewers to win (moneyline), the Brewers -1.5 run line, and the total runs bet to lean toward the over. It is also advisable to monitor any late injury or lineup changes for the Pirates, such as the status of Oneil Cruz, which could further weaken Pittsburgh’s chances.

Sources:

[1] Betting Advice Summary

[2] Brewers vs. Pirates Odds, Picks and Prediction

[3] Milwaukee Brewers vs. Pittsburgh Pirates: Odds, Picks, Predictions for 8/26/25

[4] Milwaukee Brewers vs Pittsburgh Pirates Odds, Picks and Predictions

[5] Milwaukee Brewers vs. Pittsburgh Pirates Odds, Predictions, Picks

  1. The Brewers' impressive winning streak could continue, as they are favored in the latest betting odds against the struggling Pirates.
  2. The National Football League (NFL) isn't the only league where betting is popular; major sports leagues like MLB also see significant betting activity.
  3. Betting enthusiasts might want to consider placing a bet on the Brewers to win the game, given their strong home record and dominant offensive performance during their current winning streak.
  4. The run line favors the Brewers as well, with odds for the Brewers -1.5 runs indicating they are expected to win by at least two runs.
  5. At the close of the current MLB season's news cycle, expect to find plenty of talk about the Brewers' stellar performance and their chances in the playoffs.
  6. Baseball games, like the upcoming Brewers-Pirates matchup, are prime opportunities for betting, with various lines available, such as the total runs bet, which leans toward the over in this contest.
  7. Injuries, such as the continuing absence of Pirates' shortstop Oneil Cruz, could impact Pittsburgh's chances and potentially alter betting choices in the upcoming game between the Brewers and Pirates.

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