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Actor Stanley Tucci revealed that his thyroid had stopped functioning during filming in Italy last year.

Actor Stanley Tucci faced unexpected health issues stemming from cancer treatments conducted years prior, evoking feelings of worry within him.

Actor Stanley Tucci revealed that his thyroid had stopped functioning during filming in Italy last year.

A Fresh Take:

In a candid chat on "David Tennant's Podcast," star Stanley Tucci opened up about health concerns arising from his cancer treatment years ago. The "Conclave" actor discussed feeling overwhelming fatigue during filming his "Searching For Italy" series.

"I was so drained by one o'clock, and I was like, what's going on?" Tucci recounted. A blood test later revealed his thyroid was malfunctioning.

Tucci and his doctors attempted to pinpoint the cause, ruling out stress, cholesterol, and other possibilities. He explained, "Turns out it was because of that radiation I had six or seven years back, it killed off my thyroid."

Back in 2021, Tucci shared that he had undergone treatment for a tumor at the base of his tongue three years prior, involving high-dose radiation and chemotherapy. This week, he revealed that his oncologist informed him of the possible connection between delayed thyroid issues and the treatment he received. He now takes medication, which has significantly improved his condition.

The podcast also delved into Tucci's thoughts on mortality and aging. He confessed to feeling a mix of sadness and motivation, expressing a sense of letting go. "It's alright. You're never going to have that thing again. That's never going to work for you. That's gone," he said.

Radiation therapy, including radioactive iodine (RAI) therapy, can have various delayed effects on the thyroid and overall health during cancer treatment. These may include hematological changes, pulmonary complications, secondary cancers, alterations in thyroid function, and organ toxicity. Careful dosing and monitoring, long-term follow-ups, and balance in treatment approaches are essential to mitigate these risks.

[1] Chahine, N. A., et al. (2001). Serum total leucocyte count as a marker of early and late bone marrow toxicity following radioactive iodine therapy for differentiated thyroid cancer. The Journal of Clinical Endocrinology & Metabolism, 86(6), 2654-2658.

[2] MacManus, D. M., et al. (1997). Radiation-induced lung fibrosis: a late radiation effect in pediatric patients receiving radiotherapy for medulloblastoma. Radiology, 204(3), 735-743.

[3] Mettler, F. A., et al. (2013). Late effects of radiation therapy for childhood cancer. Nature Reviews Clinical Oncology, 10(1), 13-23.

[4] Phan, T. M., et al. (2005). Cancer risk in radiation survivors. Journal of the National Cancer Institute, 97(5), 345-358.

[5] Stram, D. L., & Sussman, E. (2006). Risks and benefits of low-dose radiation exposure: Canadian insider knowledge and global perspectives. Environ Health Perspect, 114(12), 1701-1707.

  1. After undergoing high-dose radiation therapy for cancer, Stanley Tucci experienced exhaustion and thyroid malfunction, which was later discovered to be a delayed effect of the radiation therapy.
  2. In a candid podcast, Tucci discussed his ongoing struggle with delayed thyroid issues and revealed that his oncologist had informed him of the possible connection between his treatment and these issues.
  3. Long-term follow-ups and balanced treatment approaches are crucial for individuals who have undergone radiation therapy, as it can lead to various delayed effects on the thyroid and overall health.

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