2025 NFL Week 1 Schedules: Betting Probabilities and Match-ups Analysis
Twitter, Facebook, Email## NFL Kickoff 2025
Football fanatics, buckle up! The NFL's schedule drop creates a stir every year, but this time we had a sneak peek at the NFL Week 1 Schedule 2025, hours before the league's official announcement.
Highlights of Week 1 in 2025 include the blockbuster matchup between the Chiefs vs. Chargers in Brazil, the first of seven NFL International Games. Divisional rivalries are in full force, with plenty of prime-time showdowns to whet your appetite. Who knows, maybe Thursday Night Football will surprise us, too?
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NFL Week 1 Schedule 2025
Thursday Night Football (Sept. 4)
Dallas Cowboys at Philadelphia Eagles (-7, 46.5)
Friday Night Football in Brazil (Sept. 5)
Kansas City Chiefs (-3, 44.5) vs. Los Angeles Chargers
Sunday Games (Sept. 7)
1 p.m. ET window
New York Giants at Washington Commanders (-7.5, 45.5)
Tampa Bay Buccaneers (-2.5, 47.5) at Atlanta Falcons
Carolina Panthers at Jacksonville Jaguars (-3.5, 45.5)
Miami Dolphins at Indianapolis Colts (-1.5, 45.5)
Las Vegas Raiders at New England Patriots (-3.5, 43.5)
Pittsburgh Steelers (-2.5, 41.5) at New York Jets
Cincinnati Bengals (-4.5, 44.5) at Cleveland Browns
Arizona Cardinals (-3.5, 43.5) at New Orleans Saints
4 p.m. ET window
San Francisco 49ers (-1.5, 45.5) at Seattle Seahawks
Tennessee Titans at Denver Broncos (-7.5, 43.5)
Detroit Lions at Green Bay Packers (-1.5, 47.5)
Houston Texans at Los Angeles Rams (-3.5, 44.5)
Sunday Night Football
Baltimore Ravens at Buffalo Bills (-1.5, 51.5)
Monday Night Football (Sept. 8)
Minnesota Vikings at Chicago Bears (-1.5, 45.5)
Odds courtesy of DraftKings Sportsbook; find the latest odds in our NFL Betting Splits
NFL Week 1 Schedule 2025 Nuggets
Takeaways from Week 1:
Cowboys at Eagles: These NFC East titans will face off on September 4, their earliest meeting since 2008.
Chiefs vs. Chargers: The Chiefs and Chargers play in Brazil on September 5, the first NFL game ever in South America.
Giants at Commanders: This is one of two Week 1 games between a playoff team and last-place team. Washington's eight remaining games are all standalone games.
Buccaneers at Falcons: The Buccaneers lost to the Falcons in both 2024 head-to-head meetings.
Panthers at Jaguars: Two expansion teams unite for their ninth meeting in franchise history.
Dolphins at Colts: Starting the season with a road game against the Colts isn't ideal for the Dolphins, who have tough early road trips.
Raiders at Patriots: Unlike the Dolphins, the Raiders get lucky with an early trip to Foxboro.
Steelers at Jets: This is the Steelers' first non-division winner from the previous season in Week 1 since 2020.
Bengals at Browns: The Browns have won six of the last seven head-to-head games against the Bengals, but have lost the last three.
Cardinals at Saints: Tyler Shough, Spencer Rattler, or Jake Haener will start for the Cardinals in week 1.
49ers at Seahawks: Teams go from worst to first often in the NFL, but it's never happened in the NFC West. This is the 49ers' chance.
Titans at Broncos: The Titans face Drew Lock and the Broncos, who have a solid defense, in week 1.
Lions at Packers: The Lions have won six of the last seven in this series.
Texans at Rams: The Texans face the Rams to start the DeMeco Ryans era.
Ravens at Bills: The Bills and Ravens meet again in a playoff rematch, with the Bills winning 27-25. Mark Andrews' dropped pass in the final game of 2024 may fuel revenge for the Ravens.
Vikings at Bears: J.J. McCarthy may make his first NFL start in this Chicago showdown. The Bears have a limited number of standalone games.
- Football enthusiasts can enhance their sports betting experience by upgrading to VSiN Pro for access to expert picks and NFL betting odds.
- Among the NFL Week 1 Schedule 2025 highlights is the blockbuster matchup between the Chiefs and Chargers, playing in Brazil, marking the first NFL game ever in South America.
- In the NFL, divisional rivalries are in full force, with the Cowboys facing the Eagles in Week 1, their earliest meeting since 2008.
